As mentioned earlier, the MS progression and demyelinated lesions have been correlated with increased CBV and vasodilation, which could be caused by the increased endothelial cell proliferation and high levels of vascular endothelial growth factor (VEGF) and VEGF receptors (102) that are associated with the MS population compared to normal controls (103, 104). The gene discussed is VEGFA; the disease is myeloid sarcoma.