In the patients, with regard to the type of depression and the disease's state, we found several significant dependencies: rs2119882 and ASMT (p = 0.0012), rs3760138 and MEL (p = 0.0330), rs762551 and AANAT (p = 0.0022), rs3760138 and AANAT (p = 0.0094), rs12506228 and AANAT (p = 0.0269), and rs1056836 and ASMT (p = 0.0267) (Supplementary Excel File_1-Spearman's Rank Correlation). This evidence concerns the gene ASMT and depressive disorder.