Zhang et al. (2020) extracted a water-soluble polysaccharide FVP from F. velutipes, and found that FVP treatment could improve the DSS-induced colitis manifestations and epithelial mucous damage in vivo. The MPO and NO released by neutrophils in colonic inflammatory tissues were significantly inhibited by FVP. FVP also exhibited antioxidant capacity via decreasing the plasma DAO level, increasing intestinal SOD activity in DSS-induced colitis mice. Here, SOD1 is linked to colitis.