In tumor tissues from galangin treated mice, the ratios of p-JAK2/JAK2 and p-STAT3/STAT3, as well as the protein expressions of Bcl-2, caspase-3 and Ki67 were all reduced remarkably (Figures 9E,F, p < 0.01 or p < 0.001). This evidence concerns the gene CASP3 and neoplasm.