Alzheimer’s disease (AD) is typically characterized by senile plaques because of deposition of Aβ peptide, neurofibrillary tangles by hyperphosphorylation of Tau protein, and brain atrophy due to neuron loss (Hardy, 2009; Henry et al., 2013; Busche and Hyman, 2020). This evidence concerns the gene MAPT and Alzheimer disease.