Moreover, recent studies revealed FPR-1 played a critical role in regulating lung inflammation and injuries in bronchopulmonary dysplasia and it also has been demonstrated that FPR-1 can reduce lung injury by mediating neutrophil recruitment in endotoxin-induced ALI (Grommes et al., 2014; Kim et al., 2018). This evidence concerns the gene FPR1 and acute respiratory distress syndrome.