Ueta et al. reported that cold medicine (including NSAIDs and multi-ingredient cold medications)-induced SJS/TEN with SOC was strongly associated with HLA-A*02:06 (OR = 5.6) and HLA-B*44:03 (OR = 1.99) in Japanese patients (Ueta et al., 2014a). The gene discussed is HLA-B; the disease is toxic epidermal necrolysis.