HLA-B and toxic epidermal necrolysis: In Thai population, HLA-B*15:02, HLA-B*56:02, HLA-B*38:02, and HLA-B*46:01 were observed to be associated with phenytoin-induced SJS/TEN (Locharernkul et al., 2008; Tassaneeyakul et al., 2016; Sukasem et al., 2020b; Manuyakorn et al., 2020).