GFAP and astrocytic tumor: This receptor has also been linked to MAPK and the inflammatory response in astroglioma U-87 cells, where its activation with its highly potent agonist WKYMVm induces JNK and ERKs phosphorylation and increases the expression of glial fibrillary acidic protein (GFAP) and IL-1β, which are correlated with astrogliosis (Kam et al., 2007).