GPR37 and nervous system disorder: Interestingly, GPR37, also known as Parkin-associated endothelin-like receptor (Pael-R) was originally discovered through genomic library screening to find new neuropeptide receptors (Marazziti et al., 1997) and is associated with neurological disorders, such as Parkinson’s disease (PD), and autism (Lopes et al., 2015).