As for TNBC, in which Aurora-A plays a pivotal role in maintenance of cancer cell proliferation in concert with FOXM1, the kinase is important for the tumour growth of high-risk MYCN-amplified neuroblastoma, a subtype of neuroblastoma in which the MYCN gene amplification is predictive of higher aggressiveness and poor outcome [50–52]. The gene discussed is FOXM1; the disease is neoplasm.