ATRA has a role in downregulation of pin1 (Peptidylpropyl Cis/Trans Isomerase, NIMA-Interacting 1) in acute myeloid leukaemia (AML)41. Surprisingly, pin1 physically interacts with myc and both pin1 and myc are overexpressed in multiple cancers42. This evidence concerns the gene MYC and acute myeloid leukemia.