TOP3A and Bloom syndrome: abl1 (v-abl Abelson murine leukaemia viral oncogene homolog 1), myc, max (myc-associated factor X), myb, pcna (Proliferating cell nuclear antigen), top3a (Topoisomerase 3α), p73, and blm (Bloom syndrome); molecular aberrations of which are known to be associated with malignant transformation (as per the mutational profiling) (Supplementary Links and Table S1–S8).