As the relative abundance of c-9, t-11-CLA-LPC in the hippocampus was approximately 100-fold higher than that in the cortex (Fig. 7, left panel), this may be related to the stronger effects of c-9, t-11-CLA feeding on AD pathology in the hippocampus than in the cortex. The gene discussed is SELPLG; the disease is Alzheimer disease.