PARP12 and hepatocellular carcinoma: For example, overexpression of C1QTNF6 was found in gastric carcinoma23 (although it has been reported that the C1QTNF6 protein significantly suppresses the proliferation of oral squamous cell carcinoma cells)24; PARP12 upregulation was associated with the inhibition of metastasis in hepatocellular carcinoma cell lines25.