CLEC9A and neoplasm: As DNGR-1 is a cell surface receptor that possibly senses necrosis in the tumor context, this interaction could be blocked by the use of anti-DNGR-1-blocking antibodies.11 20 23 We pretreated WT mice with FL and, 1 day later, inoculated them subcutaneously with B16F10 or MC38 tumors.