CD8A and neoplasm: To directly address a potential role for DNGR-1 in cross-presentation of TAAs, WT and Clec9agfp/gfp mice were injected with B16OVA tumors and, at day 13 after tumor inoculation, we purified antigen-presenting subpopulations from tumors and TdLNs and cocultured them ex vivo with OVA-specific CD8+ T (OTI) cells.