In addition, ELISA assessment of IL-17A levels (Fig. 7b) and RT-qPCR and Western blot to determine the RORγt expression patterns (Fig. 7c, d) showed IL-17A levels and RORγt expression were elevated in the asthma mice and the mice with overexpressed YAP, overexpressed HIF-1α, or overexpressed miR-182, which was inhibited by EGR2 overexpression (p < 0.05). The gene discussed is IL17A; the disease is asthma.