CCL5 and synovitis: Following synovitis, CCL5 concentrations were increased from baseline at 6, 12, and 72 h and were greater in the synovitis joint as compared to the contralateral MCJ at 6, 72, and 168 h (synovitis CCL5 baseline: 167 ± 160 pg/mL; synovitis CCL5 peak: 634 ± 159 pg/mL, p = 0.0001) (Fig. 5e).