MKI67 and neoplasm: A higher rate of pCR after NAC was found in patients with tumour size ≤5 cm (P = 0.006), no lymph node involvement (P <  0.001), negative HR status (P <  0.001), molecular subtype as HR(−)HER2(+) or HR(−)HER2(−) (P <  0.001), Ki67 index > 14% (P <  0.001) and low Fib level (P <  0.001).