TREM2 and neoplasm: The survival rate of tumor-bearing WT mice injected with TREM2-Ig was 14.2%, which was significantly lower than that of tumor-bearing WT mice injected with hu-Ig (42.8%), tumor-bearing TREM2-TG mice injected with TREM-Ig (71.4%), and tumor-bearing TREM2-TG mice injected with hu-Ig (100%) on day 38 (Fig. 4b).