Consistent with histological analysis, we determined that infection with Δami1 significant decreased recruitment of alveolar macrophages, CD11b+ DC, neutrophils and monocytes (Figure 3(d)) with a concomitant decrease in total CD4+ T cells, CD8+ T cells, effector CD4+ T cells as well as naïve, effector and memory CD8+ T cells (Figure 3(e)), when compared to WT Mtb. Here, CD4 is linked to infection.