Interestingly, a study in 4,200 North Indians that had examined 207 common genetic variants in proximal promoter and untranslated regions of genes on 1q21–23 and 20q13 identified omentin SNP rs1333062 as one of the top signals for T2D [38]; this SNP in the 3’ flank region of omentin gene is in complete LD with Val109Asp—SNP rs2274907 (D’ = 1.0 and r2 = 1.0 for Gujarati Indians in Houston, Texas population from HapMap data). Here, ITLN1 is linked to type 2 diabetes mellitus.