The average duration of treatment before the onset of hypophysitis was 9.0 wk (range, 8.5–9.5 wk) for the combination therapy, 20.5 wk (range, 12.3–36.3 wk) for the PD-1 inhibitor therapy, and 54.0 wk (range, 53.0–55.0 wk) for the PD-L1 inhibitor therapy. The gene discussed is CD274; the disease is hypophysitis.