To further analyze the effect of EPHA/EFNA according to the BrCa subtype, the prognostic value of EPHA/EFNA family members was assessed in BrCa patients with different molecular subtypes, including basal-like, luminal A, luminal B, and HER2+ subtypes according to the 2011 St. The gene discussed is ERBB2; the disease is invasive breast carcinoma.