Silencing of KDM5C in breast cancer cells inhibited cell migration and invasion, which was due to the release of repression on its target gene BRMS1, a metastasis suppressor.[18] Recently, upregulated expression of KDM5C in breast cancer cells was reported to suppress the expression of STING and thus type I IFNs and ISGs, through which cells escape from immuno‐surveillance. The gene discussed is KDM5C; the disease is breast cancer.