The two main pathological hallmarks of AD are the deposition of extracellular plaques in the cerebral neuropil and intraneuronal neurofibrillary tangles (NFTs).[35] Amyloid‐β (Aβ) peptide and phosphorylated tau protein (p‐tau) are the primary components of the plaques and tangles, respectively. The gene discussed is MAPT; the disease is Alzheimer disease.