LRP1 and glioma: ANG/PEG‐UCNPs can sequentially target the LRP on both BBB and glioma cells, leading to precise localization and enhanced accumulation at glioma site (Figure 5A).[161] As a consequence, ANG/PEG‐UCNPs functioned as a magnetic imaging/fluorescence imaging agent and showed an improved imaging performance at glioma site compared to clinically used single MRI contrast (Gd‐DTPA) and fluorescent dye (5‐ALA).