LDLR and central nervous system cancer: developed an ApoE peptide (LRKLRKRLL)2C‐decorated chimeric polymersomes (CP) (ApoE‐CP) for targeting delivery of therapeutic protein to glioma (Figure 10A).[140] ApoE peptide, a tandem dimer sequence of the receptor‐binding domain of ApoE, was reported to possess high affinity to multiple LDLR members, such as LDLR, LRP‐1, and LRP‐2 without interfering with endogenous ApoE.