TF and central nervous system cancer: Inspired by this strategy, our group further developed DOX‐loaded DGL with acid‐cleavable Tf coating outside by long‐chain PEG and MAN decorating inside by short‐chain PEG (DD‐MCT) for targeted glioma treatment (Figure 3A).[96] Encouragingly, DD‐MCT meets the requirements at each step of the CRITID delivery cascade.