Among the identified 13 genes (ADAT3, TMEM171, DCBLD2, MARCKS, CLIP4, CTNNAL1, PIP4K2A, ZBTB10, NRP1, CST6, PLTP, CD109, and JAZF1) in our study, overexpression of MARCKS, CLIP4, NRP1, PLTP, CD109 has been previously associated with poor prognosis of GC 19-23. This evidence concerns the gene CST6 and gastric cancer.