Similar to our results, Daniel Triner et al. reported that myc-associated zinc finger (MAZ) protein regulated the proinflammatory response in colon cancer via STAT3 signaling 32, and Vikas Verma et al. reported that the activity of JAK-STAT signaling pathway was affected by artificially altering the expression level of ZNF143 33. The gene discussed is ZNF143; the disease is malignant colon neoplasm.