Although there was no statistically significant difference in terms of MGMT staining types, as seen in Table 5, although there was no significant difference in MGMT staining patterns between papillary carcinoma cases and chronic thyroiditis cases, papillary carcinoma cases mostly showed nuclear and cytoplasmic, colloidal goiter cases mostly showed nuclear staining. The gene discussed is MGMT; the disease is thyroid gland papillary carcinoma.