Moreover, a recent study conducted by Varakantham et al. suggested the sex-specific role of CYP24A1 genetic variants related to vitamin D metabolism and reported that the risk of hypertension is increased in men with the rs2762939 CC variant; however, this risk of hypertension is decreased in women with the rs2762939 CC variant. The gene discussed is CYP24A1; the disease is hypertensive disorder.