In breast cancer, three autoantibodies (PDHX, STK39, and OTUD6B) identified in TgMMTV-neu mice could also predict women who were going to develop breast cancer as compared to women, who do not develop breast cancer over 150 days prior to the detection of the breast tumor with AUC 0.68 (95% CI 0.56–0.787 p = 0.0003)33. This evidence concerns the gene PDHX and breast cancer.