Nonetheless, we provide acute and convalescent populations of rare HA306-318-specific CD4+ T cells in H3N2-infected patients that were HLA-DR*01:01+ (n = 3), HLA-DR*04:01+ (n = 1) or HLA-DR*11:01+ (n = 1), which complements other studies assessing cells in HLA-DR*04:01+ healthy donors and rheumatoid arthritis patients following influenza vaccination47,48. This evidence concerns the gene CD4 and influenza.