Secondly, hospitalized influenza-patients had increased IL-6, IL-8, MIP-1α/β and IFN-γ inflammatory cytokines, which strongly positively correlated with each other and were associated with lower influenza-specific responses from CD8+ T cells, CD4+ T cells, NK cells, MAIT and γδT cells, and lower ASC and Tfh responses. Here, CD4 is linked to influenza.