Moreover, bioinformatics analysis of the databases of GEO, EGA, and TCGA using the Kaplan–Meier plotter (https://kmplot.com/analysis/index.php?p=service&cancer=breast) showed that low expression of PPP3CB, as compared to high PPP3CB expression, significantly associated with a worse overall survival (OS), relapse-free survival (RFS), and distant metastasis-free survival (DMFS) in breast cancer patients (Fig. 7e). Here, PPP3CB is linked to breast cancer.