We also obtained similar results in experiments testing the cytotoxicity of CD8 T cells and Treg cells derived from human peripheral blood mononuclear cells (PBMCs) against human GBM tumor cells—MGG4 and MGG8 that are known to recapitulate human GBM features56—in the presence of αPD1 + αGITR antibodies (Fig. 4g, h). The gene discussed is CD8A; the disease is glioblastoma.