We also obtained similar results in experiments testing the cytotoxicity of CD8 T cells and Treg cells derived from human peripheral blood mononuclear cells (PBMCs) against human GBM tumor cells—MGG4 and MGG8 that are known to recapitulate human GBM features56—in the presence of αPD1 + αGITR antibodies (Fig. 4g, h). This evidence concerns the gene CD8A and neoplasm.