In BALB/c mice bearing B7H3-WT re-expressed 4T1-B7H3KO xenograft tumors, however, the combined treatment with 2F-Fuc and anti-PDL1 significantly improved tumor growth inhibition, as confirmed by the growth curves of the xenograft tumor volumes and the tumor weights (Fig. 8d). This evidence concerns the gene CD274 and neoplasm.