It has been reported that Mcl-1 is the target gene of transcription factor STAT3 implicated in tumor survival.13 In addition, STAT3 is a critical downstream of DDR1 signaling,14 we, therefore, hypothesized that STAT3 may be a mediator between DDR1 and Mcl-1 in UM. The gene discussed is MCL1; the disease is neoplasm.