CBR3 and cardiomyopathy: In a later study looking at a larger cohort of survivors with and without cardiomyopathy, we found that even at low doses of anthracycline (1–250 mg/m2) patients with CBR3 GG genotypes had a higher risk of cardiomyopathy when compared with individuals with CBR3 GA/AA genotypes unexposed to anthracyclines (OR = 5.5, p = 0.003), or exposed to < 250 mg/m2 (OR = 3.3, p = 0.006) [3].