The Global Initiative for Asthma (GINA) has highlighted corticosteroids and biological therapies (e.g., anti-IgE antibody, anti-interleukin-5/5Rα, and anti-interleukin-4Rα) in their guidelines for asthma treatment [3]; however, these treatments primarily target Th2-mediated airway inflammation. Here, IGHE is linked to asthma.