Family history revealed that her father (Individual 1B) also exhibits bilateral microphthalmia, aniridia, ectopia lentis, and microcornea; research exome analysis and Sanger sequencing identified the same heterozygous c.152G>T p.(Arg51Leu) variant in the father and wild‐type MAB21L1 alleles in the unaffected mother (Figure 1b). The gene discussed is MAB21L1; the disease is isolated aniridia.