B-ALL cases with recurrent genetic abnormality (RGA) t(12;21)(p13;q22) TEL-AML1 (ETV6-RUNX1) revealed blast cell positivity for CD19, CD10, CD34, and CD13 but were typically negative for CD20, CD9, CD66c. The gene discussed is CEACAM6; the disease is acute lymphoblastic leukemia.