A wide range of zebrafish models could be suitable for our automated system, such as the established gene-disruption models of C9orf72, TDP43 and SOD1 (Lissouba et al., 2018; Robinson et al., 2019) for ALS, and the neurexin mutants for SMA (Koh et al., 2020). The gene discussed is TARDBP; the disease is amyotrophic lateral sclerosis.