This discrepancy with literature data indicating expected solely LH activity during conventional (salient) metaphors and idioms processing (Bohrn et al. 2012; Rapp et al., 2012; Reyes-Aguilar et al. 2018) may be assumed as an effect of the design of the punchline-based task, and/or more specifically to Polish language characteristics, but further research on both conventional and novel metaphors processing in schizophrenia is required to resolve this question. This evidence concerns the gene PLOD1 and schizophrenia.