IRF7 expression was decreased by 17% in autoantibody-positive individuals (p = 6.10 × 10−3, 95% CI 0.02, 0.14, Fig. 3c); the expression of this gene was increased in longstanding type 1 diabetes by 14% (p = 4.00 × 10−2, 95% CI −0.11, −0.002, Fig. 3c). The gene discussed is IRF7; the disease is type 1 diabetes mellitus.