None of the patients carried PD-causing Mendelian mutations, nevertheless, we found heterozygous patients for rare variants in NR4A2 (Nuclear Receptor Subfamily 4 Group A Member 2), in ATP7B (ATPase, Cu(2+)-transporting, beta polypeptide), GBA (Glucosidase, beta, acid) and LRRK2 (Table S3). This evidence concerns the gene NR4A2 and Parkinson disease.