Tumor tissue from relapsed refractory gastric/gastroesophageal junction (G/GEJ) patients that received a DKN-01 + pembrolizumab combination treatment as part of a phase 1b/2a study were retrospectively investigated for DKK1 mRNA levels using the RNAscope chromogenic in situ hybridization (CISH) assay24. This evidence concerns the gene DKK1 and neoplasm.