VIM and cancer: For this, we combined three gene sets which represent complementary definitions for EMT-related genes (Fig. 1a): (1) the MSigDB Hallmark EMT gene set34,35, which is based on consensus across many EMT-related gene sets; (2) the EMT signature genes from Tan et al.36, selected due to their consistency with the EMT program across many cancer types; and (3) genes that correlate highly in bulk RNA-seq data with classical EMT markers (Vimentin and the 5 EMT TFs).