PPARA and skin basal cell carcinoma: Down-regulated KEGG pathways in BCC tumors included peroxisome proliferator–activated receptor (PPAR) signalling (P = 3.0 × 10−11), metabolic pathways (P = 5.4 × 10−09), fatty acid metabolism (P = 6.3 × 10−06), and retinol metabolism (P = 1.5 × 10−05) (Fig 2A and Table S5), indicating an overrepresentation of lipid metabolic pathways.