We queried gene expression for twelve known PAH risk genes (ACVRL1, BMPR2, CAV1, EIF2AK4, ENG, KCNK3, KDR, NOTCH1, SMAD4, SMAD9, SOX17, TBX4) and the two new candidate risk genes (FBLN2, PDGFD). This evidence concerns the gene FBLN2 and pulmonary arterial hypertension.