In order to further investigate the correlation between FLI1 and CCL3 that caused the migration of melanoma cells, we conducted a rescue experiment by adding exogenous CCL3 into the co-culture system, the result shows that exogenous CCL3 reverse the inhibit effect of tumor cell migration that siFLI1 conducted (Additional file 1: Figure S1C–E). The gene discussed is FLI1; the disease is melanoma.