DHODH and acute myeloid leukemia: The overexpression of DHODH are observed in multiple malignance cells, including AML [60], skin cancer [61], colorectal cancer (CRC) [62], pancreatic cancer [63], breast cancer [56], lung cancer [64], multiple myeloma cells [65], neuroblastoma cells [48], renal cell carcinoma (RCC) [49], cervical cancer [50], and glioblastoma stem cells (GSCs) [25].