Apoptosis results were displayed in Fig. 6f, g, compared with the control group, the cell apoptotic rates was markedly decreased after HGC-27 exosome treatment (Fig. 6f); in addition, the qRT-PCR results showed that, after exosome treatment, increased expression of Bcl-2 and decreased expression of Bax were observed(Fig. 6g); in Fig. 6j, Western blot results showed that up-regulated expression of Bcl-2 was found in MKN45 cells treated by exosomes, revealing that the treatment of exosomes could inhibit the apoptosis of GC cells. The gene discussed is BAX; the disease is gastric cancer.