Apoptosis results were displayed in Fig. 5f, g, compared with the control group, the cell apoptotic rates was markedly decreased after FRLnc1 overexpression (Fig. 5f); in addition, the qRT-PCR results showed that, after FRLnc1 overexpression, increased expression of Bcl-2 and decreased expression of Bax were observed (Fig. 5g); in Fig. 5j, Western blot results showed that up-regulated expression of Bcl-2 was found in MKN45 cells treated by FRLnc1 overexpression, revealing that the treatment of FRLnc1 overexpression could inhibit the apoptosis of GC cells. The gene discussed is BAX; the disease is gastric cancer.