ZFAS1 and gastric cancer: In addition, Zhou et al. [24] demonstrated that lncRNA ZFAS1 was significantly up-regulated in 66 cases of GC tissues compared with normal tissues, and up-regulated lncRNA ZFAS1 was correlated to TNM stage, tumor invasion, LNM and tumor diameter; moreover, up-regulated lncRNA ZFAS1 was also found in plasma of GC patients, and the highly-expressed ZFAS1 in plasma was correlated to TNM Stage, LNM and distant metastasis.