Forkhead box protein M1 (FOXM1), a transcription factor characterized by a 100 amino acid winged-helix DNA binding domain, plays im-portant roles in the regulation of oncogenesis and tumor progression in malignancies, forkhead box protein M1 (FOXM1) is one of the members of the family of evolutionarily conserved transcriptional factors characterized by the presence of a DNA-binding domain called the forkhead box or winged helix domain [5–7]. The gene discussed is FOXM1; the disease is neoplasm.