Our research expanded on a previous cross-sectional study investigating the correlation between changes in GGT levels and IR and related metabolic dysfunction for the first time, and our study provided novel findings that the degree of IR decrease to normal and other related indexes that were reduced to target levels by treatment are potential predictors of restored GGT levels, suggesting that the clinical value of GGT differs from ALT as a noninvasive monitoring parameter to directly estimate the posttreatment severity of NAFLD [11]. This evidence concerns the gene GPT and metabolic dysfunction-associated steatotic liver disease.