Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analyses demonstrated that the inflammatory response and type II diabetes mellitus were enriched in SSD, and 5'-nucleotidase domain containing 1 (NT5DC1), Small G protein signaling modulator 2 (SGSM2) and MYC binding protein (MYCBP) were ultimately identified as significant hub genes. The gene discussed is MYCBP; the disease is type 2 diabetes mellitus.